Descubre la genética que hace de ti una persona única
El equipo de genetistas de Mendel ha identificado variaciones genéticas asociadas a estas características psicológicas con una estadística significativa (p-valor < 1×10-8)
Adicciones
Adicciones
Estudios académicos
Frank, J., Cichon, S., Treutlein, J., Ridinger, M., Mattheisen, M., Hoffmann, P., Herms, S., Wodarz, N., Soyka, M., Zill, P., Maier, W., Mössner, R., Gaebel, W., Dahmen, N., Scherbaum, N., Schmäl, C., Steffens, M., Lucae, S., Ising, M., Müller-Myhsok, B., … Rietschel, M. (2012). Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster. Addiction biology, 17(1), 171–180. https://doi.org/10.1111/j.1369-1600.2011.00395.x
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Estudios académicos
Lind PA, Zhu G, Montgomery GW, Madden PA, Heath AC, Martin NG, Slutske WS. Genome-wide association study of a quantitative disordered gambling trait. Addict Biol. 2013 May;18(3):511-22. doi: 10.1111/j.1369-1600.2012.00463.x. Epub 2012 Jul 11. PMID: 22780124; PMCID: PMC3470766.
Genética
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Estudios académicos
Liu, M., Jiang, Y., Wedow, R., Li, Y., Brazel, D. M., Chen, F., Datta, G., Davila-Velderrain, J., McGuire, D., Tian, C., Zhan, X., 23andMe Research Team, HUNT All-In Psychiatry, Choquet, H., Docherty, A. R., Faul, J. D., Foerster, J. R., Fritsche, L. G., Gabrielsen, M. E., Gordon, S. D., … Vrieze, S. (2019). Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use. Nature genetics, 51(2), 237–244. https://doi.org/10.1038/s41588-018-0307-5
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Estudios académicos
Cox, J., Sherva, R., Wetherill, L., Foroud, T., Edenberg, H. J., Kranzler, H. R., Gelernter, J., & Farrer, L. A. (2021). Genome-wide association study of stimulant dependence. Translational psychiatry, 11(1), 363. https://doi.org/10.1038/s41398-021-01440-5
Genética
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Estudios académicos
Sanchez-Roige, S., Fontanillas, P., Elson, S. L., Gray, J. C., de Wit, H., MacKillop, J., & Palmer, A. A. (2019). Genome-Wide Association Studies of Impulsive Personality Traits (BIS-11 and UPPS-P) and Drug Experimentation in up to 22,861 Adult Research Participants Identify Loci in the CACNA1I and CADM2 genes. The Journal of neuroscience : the official journal of the Society for Neuroscience, 39(13), 2562–2572.
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Estudios académicos
Tobacco and Genetics Consortium (2010). Genome-wide meta-analyses identify multiple loci associated with smoking behavior. Nature genetics, 42(5), 441–447. https://doi.org/10.1038/ng.571
Genética
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Estudios académicos
David, S. P., Hamidovic, A., Chen, G. K., Bergen, A. W., Wessel, J., Kasberger, J. L., Brown, W. M., Petruzella, S., Thacker, E. L., Kim, Y., Nalls, M. A., Tranah, G. J., Sung, Y. J., Ambrosone, C. B., Arnett, D., Bandera, E. V., Becker, D. M., Becker, L., Berndt, S. I., Bernstein, L., … Furberg, H. (2012). Genome-wide meta-analyses of smoking behaviors in African Americans. Translational psychiatry, 2(5), e119. https://doi.org/10.1038/tp.2012.41
Genética
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Curiosidades
Curiosidades
Estudios académicos
Cuellar-Partida, G., Tung, J. Y., Eriksson, N., Albrecht, E., Aliev, F., Andreassen, O. A., Barroso, I., Beckmann, J. S., Boks, M. P., Boomsma, D. I., Boyd, H. A., Breteler, M., Campbell, H., Chasman, D. I., Cherkas, L. F., Davies, G., de Geus, E., Deary, I. J., Deloukas, P., Dick, D. M., … Medland, S. E. (2021). Genome-wide association study identifies 48 common genetic variants associated with handedness. Nature human behaviour, 5(1), 59–70. https://doi.org/10.1038/s41562-020-00956-y
Genética
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Estudios académicos
Markt, S. C., Nuttall, E., Turman, C., Sinnott, J., Rimm, E. B., Ecsedy, E., Unger, R. H., Fall, K., Finn, S., Jensen, M. K., Rider, J. R., Kraft, P., & Mucci, L. A. (2016). Sniffing out significant “Pee values”: genome wide association study of asparagus anosmia. BMJ (Clinical research ed.), 355, i6071. https://doi.org/10.1136/bmj.i6071
Genética
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Estudios académicos
Wolber, L. E., Girotto, G., Buniello, A., Vuckovic, D., Pirastu, N., Lorente-Cánovas, B., Rudan, I., Hayward, C., Polasek, O., Ciullo, M., Mangino, M., Steves, C., Concas, M. P., Cocca, M., Spector, T. D., Gasparini, P., Steel, K. P., & Williams, F. M. (2014). Salt-inducible kinase 3, SIK3, is a new gene associated with hearing. Human molecular genetics, 23(23), 6407–6418. https://doi.org/10.1093/hmg/ddu346
Genética
Ambiente
Estudios académicos
Cuellar-Partida, G., Tung, J. Y., Eriksson, N., Albrecht, E., Aliev, F., Andreassen, O. A., Barroso, I., Beckmann, J. S., Boks, M. P., Boomsma, D. I., Boyd, H. A., Breteler, M., Campbell, H., Chasman, D. I., Cherkas, L. F., Davies, G., de Geus, E., Deary, I. J., Deloukas, P., Dick, D. M., … Medland, S. E. (2021). Genome-wide association study identifies 48 common genetic variants associated with handedness. Nature human behaviour, 5(1), 59–70. https://doi.org/10.1038/s41562-020-00956-y
Genética
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Estudios académicos
Randall CL, Wright CD, Chernus JM, McNeil DW, Feingold E, Crout RJ, Neiswanger K, Weyant RJ, Shaffer JR, Marazita ML. A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain. Pain Res Manag. 2017;2017:7375468. doi: 10.1155/2017/7375468. Epub 2017 Jun 15. PMID: 28701861; PMCID: PMC5494109.
Genética
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Estudios académicos
Reimann, F., Cox, J. J., Belfer, I., Diatchenko, L., Zaykin, D. V., McHale, D. P., Drenth, J. P., Dai, F., Wheeler, J., Sanders, F., Wood, L., Wu, T. X., Karppinen, J., Nikolajsen, L., Männikkö, M., Max, M. B., Kiselycznyk, C., Poddar, M., Te Morsche, R. H., Smith, S., … Woods, C. G. (2010). Pain perception is altered by a nucleotide polymorphism in SCN9A. Proceedings of the National Academy of Sciences of the United States of America, 107(11), 5148–5153. https://doi.org/10.1073/pnas.0913181107
Genética
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Estudios académicos
Keller, A., Zhuang, H., Chi, Q., Vosshall, L. B., & Matsunami, H. (2007). Genetic variation in a human odorant receptor alters odour perception. Nature, 449(7161), 468–472. https://doi.org/10.1038/nature06162
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Estudios académicos
Eriksson, N., Macpherson, J. M., Tung, J. Y., Hon, L. S., Naughton, B., Saxonov, S., Avey, L., Wojcicki, A., Pe’er, I., & Mountain, J. (2010). Web-based, participant-driven studies yield novel genetic associations for common traits. PLoS genetics, 6(6), e1000993. https://doi.org/10.1371/journal.pgen.1000993
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Estudios académicos
Meddens, S., de Vlaming, R., Bowers, P., Burik, C., Linnér, R. K., Lee, C., Okbay, A., Turley, P., Rietveld, C. A., Fontana, M. A., Ghanbari, M., Imamura, F., McMahon, G., van der Most, P. J., Voortman, T., Wade, K. H., Anderson, E. L., Braun, K., Emmett, P. M., Esko, T., … Koellinger, P. D. (2021). Genomic analysis of diet composition finds novel loci and associations with health and lifestyle. Molecular psychiatry, 26(6), 2056–2069. https://doi.org/10.1038/s41380-020-0697-5
Genética
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Capacidades
Capacidades
Estudios académicos
Gialluisi, A., Andlauer, T., Mirza-Schreiber, N., Moll, K., Becker, J., Hoffmann, P., Ludwig, K. U., Czamara, D., St Pourcain, B., Brandler, W., Honbolygó, F., Tóth, D., Csépe, V., Huguet, G., Morris, A. P., Hulslander, J., Willcutt, E. G., DeFries, J. C., Olson, R. K., Smith, S. D., … Schulte-Körne, G. (2019). Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia. Translational psychiatry, 9(1), 77. https://doi.org/10.1038/s41398-019-0402-0
Genética
Ambiente
Estudios académicos
Gialluisi, A., Andlauer, T., Mirza-Schreiber, N., Moll, K., Becker, J., Hoffmann, P., Ludwig, K. U., Czamara, D., St Pourcain, B., Brandler, W., Honbolygó, F., Tóth, D., Csépe, V., Huguet, G., Morris, A. P., Hulslander, J., Willcutt, E. G., DeFries, J. C., Olson, R. K., Smith, S. D., … Schulte-Körne, G. (2019). Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia. Translational psychiatry, 9(1), 77. https://doi.org/10.1038/s41398-019-0402-0
Genética
Ambiente
Estudios académicos
Chen, H., Gu, X. H., Zhou, Y., Ge, Z., Wang, B., Siok, W. T., Wang, G., Huen, M., Jiang, Y., Tan, L. H., & Sun, Y. (2017). A Genome-Wide Association Study Identifies Genetic Variants Associated with Mathematics Ability. Scientific reports, 7, 40365. https://doi.org/10.1038/srep40365
Genética
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Estudios académicos
Savage, J. E., Jansen, P. R., Stringer, S., Watanabe, K., Bryois, J., de Leeuw, C. A., Nagel, M., Awasthi, S., Barr, P. B., Coleman, J., Grasby, K. L., Hammerschlag, A. R., Kaminski, J. A., Karlsson, R., Krapohl, E., Lam, M., Nygaard, M., Reynolds, C. A., Trampush, J. W., Young, H., … Posthuma, D. (2018). Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence. Nature genetics, 50(7), 912–919. https://doi.org/10.1038/s41588-018-0152-6
Genética
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Estudios académicos
Zabaneh, D., Krapohl, E., Gaspar, H. A., Curtis, C., Lee, S. H., Patel, H., Newhouse, S., Wu, H. M., Simpson, M. A., Putallaz, M., Lubinski, D., Plomin, R., & Breen, G. (2018). A genome-wide association study for extremely high intelligence. Molecular psychiatry, 23(5), 1226–1232. https://doi.org/10.1038/mp.2017.121
Genética
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Estudios académicos
Debette, S., Ibrahim Verbaas, C. A., Bressler, J., Schuur, M., Smith, A., Bis, J. C., Davies, G., Wolf, C., Gudnason, V., Chibnik, L. B., Yang, Q., deStefano, A. L., de Quervain, D. J., Srikanth, V., Lahti, J., Grabe, H. J., Smith, J. A., Priebe, L., Yu, L., Karbalai, N., … Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (2015). Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium. Biological psychiatry, 77(8), 749–763. https://doi.org/10.1016/j.biopsych.2014.08.027
Genética
Ambiente
Estudios académicos
Blokland, G. A. (2017). Genome-wide association study of working memory brain activation. International Journal of Psychophysiology, 115, 98–111. https://doi.org/10.1016/j.ijpsycho.2016.09.010
Genética
Ambiente
Estudios académicos
Ramanan, V. K., Nho, K., Shen, L., Risacher, S. L., Kim, S., McDonald, B. C., Farlow, M. R., Foroud, T. M., Gao, S., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Lovestone, S., Aisen, P. S., Petersen, R. C., Jack, C. R., Jr, Shaw, L. M., Trojanowski, J. Q., … Saykin, A. J. (2015). FASTKD2 is associated with memory and hippocampal structure in older adults. Molecular psychiatry, 20(10), 1197–1204. https://doi.org/10.1038/mp.2014.142
Genética
Ambiente
Estudios académicos
Ibrahim-Verbaas, C. A., Bressler, J., Debette, S., Schuur, M., Smith, A. V., Bis, J. C., Davies, G., Trompet, S., Smith, J. A., Wolf, C., Chibnik, L. B., Liu, Y., Vitart, V., Kirin, M., Petrovic, K., Polasek, O., Zgaga, L., Fawns-Ritchie, C., Hoffmann, P., Karjalainen, J., … Mosley, T. H. (2016). GWAS for executive function and processing speed suggests involvement of the CADM2 gene. Molecular psychiatry, 21(2), 189–197. https://doi.org/10.1038/mp.2015.37
Genética
Ambiente
Estudios académicos
Gialluisi, A., Andlauer, T., Mirza-Schreiber, N., Moll, K., Becker, J., Hoffmann, P., Ludwig, K. U., Czamara, D., St Pourcain, B., Brandler, W., Honbolygó, F., Tóth, D., Csépe, V., Huguet, G., Morris, A. P., Hulslander, J., Willcutt, E. G., DeFries, J. C., Olson, R. K., Smith, S. D., … Schulte-Körne, G. (2019). Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia. Translational psychiatry, 9(1), 77. https://doi.org/10.1038/s41398-019-0402-0
Genética
Ambiente
Estudios académicos
Ibrahim-Verbaas, C. A., Bressler, J., Debette, S., Schuur, M., Smith, A. V., Bis, J. C., Davies, G., Trompet, S., Smith, J. A., Wolf, C., Chibnik, L. B., Liu, Y., Vitart, V., Kirin, M., Petrovic, K., Polasek, O., Zgaga, L., Fawns-Ritchie, C., Hoffmann, P., Karjalainen, J., … Mosley, T. H. (2016). GWAS for executive function and processing speed suggests involvement of the CADM2 gene. Molecular psychiatry, 21(2), 189–197. https://doi.org/10.1038/mp.2015.37
Genética
Ambiente
Psicología
Personalidad
Estudios académicos
De Moor, M. H., Costa, P. T., Terracciano, A., Krueger, R. F., de Geus, E. J., Toshiko, T., Penninx, B. W., Esko, T., Madden, P. A., Derringer, J., Amin, N., Willemsen, G., Hottenga, J. J., Distel, M. A., Uda, M., Sanna, S., Spinhoven, P., Hartman, C. A., Sullivan, P., Realo, A., … Boomsma, D. I. (2012). Meta-analysis of genome-wide association studies for personality. Molecular psychiatry, 17(3), 337–349. https://doi.org/10.1038/mp.2010.128
Genética
Ambiente
Estudios académicos
De Moor, M. H., Costa, P. T., Terracciano, A., Krueger, R. F., de Geus, E. J., Toshiko, T., Penninx, B. W., Esko, T., Madden, P. A., Derringer, J., Amin, N., Willemsen, G., Hottenga, J. J., Distel, M. A., Uda, M., Sanna, S., Spinhoven, P., Hartman, C. A., Sullivan, P., Realo, A., … Boomsma, D. I. (2012). Meta-analysis of genome-wide association studies for personality. Molecular psychiatry, 17(3), 337–349. https://doi.org/10.1038/mp.2010.128
Genética
Ambiente
Estudios académicos
Okbay, A., Baselmans, B. M., De Neve, J. E., Turley, P., Nivard, M. G., Fontana, M. A., Meddens, S. F., Linnér, R. K., Rietveld, C. A., Derringer, J., Gratten, J., Lee, J. J., Liu, J. Z., de Vlaming, R., Ahluwalia, T. S., Buchwald, J., Cavadino, A., Frazier-Wood, A. C., Furlotte, N. A., Garfield, V., … Cesarini, D. (2016). Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nature genetics, 48(6), 624–633. https://doi.org/10.1038/ng.3552
Genética
Ambiente
Estudios académicos
De Moor, M. H., Costa, P. T., Terracciano, A., Krueger, R. F., de Geus, E. J., Toshiko, T., Penninx, B. W., Esko, T., Madden, P. A., Derringer, J., Amin, N., Willemsen, G., Hottenga, J. J., Distel, M. A., Uda, M., Sanna, S., Spinhoven, P., Hartman, C. A., Sullivan, P., Realo, A., … Boomsma, D. I. (2012). Meta-analysis of genome-wide association studies for personality. Molecular psychiatry, 17(3), 337–349. https://doi.org/10.1038/mp.2010.128<br />
Amin, N., Hottenga, J. J., Hansell, N. K., Janssens, A. C., de Moor, M. H., Madden, P. A., Zorkoltseva, I. V., Penninx, B. W., Terracciano, A., Uda, M., Tanaka, T., Esko, T., Realo, A., Ferrucci, L., Luciano, M., Davies, G., Metspalu, A., Abecasis, G. R., Deary, I. J., Raikkonen, K., … van Duijn, C. M. (2013). Refining genome-wide linkage intervals using a meta-analysis of genome-wide association studies identifies loci influencing personality dimensions. European journal of human genetics : EJHG, 21(8), 876–882. https://doi.org/10.1038/ejhg.2012.263
Genética
Ambiente
Estudios académicos
De Moor, M. H., Costa, P. T., Terracciano, A., Krueger, R. F., de Geus, E. J., Toshiko, T., Penninx, B. W., Esko, T., Madden, P. A., Derringer, J., Amin, N., Willemsen, G., Hottenga, J. J., Distel, M. A., Uda, M., Sanna, S., Spinhoven, P., Hartman, C. A., Sullivan, P., Realo, A., … Boomsma, D. I. (2012). Meta-analysis of genome-wide association studies for personality. Molecular psychiatry, 17(3), 337–349. https://doi.org/10.1038/mp.2010.128<br />
Genética
Ambiente
Estrés y ansiedad
Estudios académicos
Purves, K. L., Coleman, J., Meier, S. M., Rayner, C., Davis, K., Cheesman, R., Bækvad-Hansen, M., Børglum, A. D., Wan Cho, S., Jürgen Deckert, J., Gaspar, H. A., Bybjerg-Grauholm, J., Hettema, J. M., Hotopf, M., Hougaard, D., Hübel, C., Kan, C., McIntosh, A. M., Mors, O., Bo Mortensen, P., … Eley, T. C. (2020). A major role for common genetic variation in anxiety disorders. Molecular psychiatry, 25(12), 3292–3303. https://doi.org/10.1038/s41380-019-0559-1
Genética
Ambiente
Estudios académicos
Stein, M. B., Chen, C. Y., Jain, S., Jensen, K. P., He, F., Heeringa, S. G., Kessler, R. C., Maihofer, A., Nock, M. K., Ripke, S., Sun, X., Thomas, M. L., Ursano, R. J., Smoller, J. W., Gelernter, J., & Army STARRS Collaborators (2017). Genetic risk variants for social anxiety. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 174(2), 120–131. https://doi.org/10.1002/ajmg.b.32520
Genética
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Estudios académicos
Sulkava, S., Ollila, H. M., Alasaari, J., Puttonen, S., Härmä, M., Viitasalo, K., Lahtinen, A., Lindström, J., Toivola, A., Sulkava, R., Kivimäki, M., Vahtera, J., Partonen, T., Silander, K., Porkka-Heiskanen, T., & Paunio, T. (2017). Common Genetic Variation Near Melatonin Receptor 1A Gene Linked to Job-Related Exhaustion in Shift Workers. Sleep, 40(1), zsw011. https://doi.org/10.1093/sleep/zsw011
Genética
Ambiente
Estudios académicos
Nagel, M., Jansen, P. R., Stringer, S., Watanabe, K., de Leeuw, C. A., Bryois, J., Savage, J. E., Hammerschlag, A. R., Skene, N. G., Muñoz-Manchado, A. B., 23andMe Research Team, White, T., Tiemeier, H., Linnarsson, S., Hjerling-Leffler, J., Polderman, T., Sullivan, P. F., van der Sluis, S., & Posthuma, D. (2018). Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways. Nature genetics, 50(7), 920–927. https://doi.org/10.1038/s41588-018-0151-7
Genética
Desconocido
Ambiente
Genética
Ambiente
Estudios académicos
“Rimpelä, J. M., Niiranen, T., Jula, A., Pörsti, I. H., Tikkakoski, A., Havulinna, A., Lehtimäki, T., Salomaa, V., Kontula, K. K., & Hiltunen, T. P. (2019). Genome-wide association study of white-coat effect in hypertensive patients. Blood Pressure, 28(4), 239–249. https://doi.org/10.1080/08037051.2019.1604066
Schijven, D., Geuze, E., Vinkers, C. H., Pulit, S. L., Schür, R. R., Malgaz, M., Bekema, E., Medic, J., van der Kust, K. E., Veldink, J. H., Boks, M. P., Vermetten, E., & Luykx, J. J. (2019). Multivariate genome-wide analysis of stress-related quantitative phenotypes. European Neuropsychopharmacology, 29(12), 1354–1364. https://doi.org/https://doi.org/10.1016/j.euroneuro.2019.09.012“
Genética
Ambiente
Bienestar emocional
Estudios académicos
Klein, T. A., Neumann, J., Reuter, M., Hennig, J., von Cramon, D. Y., & Ullsperger, M. (2007). Genetically determined differences in learning from errors. Science (New York, N.Y.), 318(5856), 1642–1645. https://doi.org/10.1126/science.1145044
Genética
Ambiente
Estudios académicos
Okbay, A., Baselmans, B. M., De Neve, J. E., Turley, P., Nivard, M. G., Fontana, M. A., Meddens, S. F., Linnér, R. K., Rietveld, C. A., Derringer, J., Gratten, J., Lee, J. J., Liu, J. Z., de Vlaming, R., Ahluwalia, T. S., Buchwald, J., Cavadino, A., Frazier-Wood, A. C., Furlotte, N. A., Garfield, V., … Cesarini, D. (2016). Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nature genetics, 48(6), 624–633. https://doi.org/10.1038/ng.3552
Baselmans, B., & Bartels, M. (2018). A genetic perspective on the relationship between eudaimonic -and hedonic well-being. Scientific reports, 8(1), 14610. https://doi.org/10.1038/s41598-018-32638-1
Sanchez-Roige, S., Gray, J. C., MacKillop, J., Chen, C. H., & Palmer, A. A. (2018). The genetics of human personality. Genes, brain, and behavior, 17(3), e12439. https://doi.org/10.1111/gbb.12439
Genética
Ambiente
Estudios académicos
Primes, G., & Fieder, M. (2018). Real-life helping behaviours in North America: A genome-wide association approach. PloS one, 13(1), e0190950. https://doi.org/10.1371/journal.pone.0190950
Genética
Ambiente
Estudios académicos
Meng, W., Adams, M. J., Palmer, C., 23andMe Research Team, Shi, J., Auton, A., Ryan, K. A., Jordan, J. M., Mitchell, B. D., Jackson, R. D., Yau, M. S., McIntosh, A. M., & Smith, B. H. (2019). Genome-wide association study of knee pain identifies associations with GDF5 and COL27A1 in UK Biobank. Communications biology, 2, 321. https://doi.org/10.1038/s42003-019-0568-2
Genética
Ambiente
Estudios académicos
“Warrier, V., Toro, R., Chakrabarti, B., iPSYCH-Broad autism group, Børglum, A. D., Grove, J., 23andMe Research Team, Hinds, D. A., Bourgeron, T., & Baron-Cohen, S. (2018). Genome-wide analyses of self-reported empathy: correlations with autism, schizophrenia, and anorexia nervosa. Translational psychiatry, 8(1), 35. https://doi.org/10.1038/s41398-017-0082-6
López, M. B., Arán Filippetti, V., & Richaud, M. C. (2014). Empatía: desde la percepción automática hasta los procesos controlados.
Pérez, M. C., Gerónimo, E. M., & Castilla, I. M. (2019). La inteligencia emocional y la empatía como factores predictores del bienestar subjeti